Incidence of mefA and mefE Genes in Viridans Group Streptococci
نویسندگان
چکیده
منابع مشابه
Incidence of mefA and mefE genes in viridans group streptococci.
Viridans group streptococci form the major part of the commensal flora of the human upper respiratory tract. However, these organisms are also the leading cause of infective endocarditis and an increasing source of bacteremia in neutropenic patients (1). Beta-lactam agents are the treatment of choice for these infections, but macrolides and related drugs are recommended for prophylaxis and alte...
متن کاملDistribution of subclasses mefA and mefE of the mefA gene among clinical isolates of macrolide-resistant (M-phenotype) Streptococcus pneumoniae, viridans group streptococci, and Streptococcus pyogenes.
The distribution of subclasses mefA and mefE of the mefA gene among 116 M-phenotype streptococci was as follows: pneumococci (38 strains had mefE and 4 mefA), viridans streptococci (49 mefE and 1 mefA), and Streptococcus pyogenes (24 mefA). Spain(9V)-3-14 and England(14)-9 clones of serotype 14 were dominant among pneumococci.
متن کاملEmergence of mefA and mefE genes in beta-haemolytic streptococci and pneumococci in France.
Sir, Since the early 1990s, most developed countries have experienced a rapid and substantial increase in erythromycin resistance among isolates of Streptococcus pyogenes and Streptococcus pneumoniae, probably related to the increased prescribing of this antibiotic or its novel semisynthetic derivatives. Until recently, the unique mechanism of macrolide resistance recognized in streptococci was...
متن کاملMannosidase production by viridans group streptococci.
The production of mannosidase activity by all currently recognized species of human viridans group streptococci was determined using an assay in which bacterial growth was dependent on the degradation of the high-mannose-type glycans of RNase B and subsequent utilization of released mannose. RNase B is an excellent substrate for the demonstration of mannosidase activity since it is a glycoprote...
متن کاملAntimicrobial susceptibility patterns and macrolide resistance genes of viridans group streptococci from blood cultures in Korea.
OBJECTIVES Our aim was to study the antimicrobial susceptibilities and macrolide resistance mechanisms of viridans group streptococci (VGS) in a Korean tertiary hospital. METHODS MICs of five antimicrobials were determined for 106 VGS isolated from blood cultures. The macrolide resistance mechanisms of erythromycin non-susceptible isolates were studied by the double-disc test and PCR. RESUL...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 1999
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.43.9.2335